Endocrine Abstracts

Introduction: The aging population brought new challenges in several diseases. Pituitary tumors are usually not related with elderly, although the rise in life expectancy has allowed its diagnosis in unusual age groups.Aim: To describe the pituitary tumors diagnosed in patients with age ≥ 80 yearsMethods: Retrospective observational study which included 23 patients with pituitary tumors with age ≥ 80 years observed in c...

Introduction: Turner syndrome (TS) is one of the most common chromosomal abnormalities, characterized by systemic involvement and susceptibility to some disorders that begin or progress in adult life. These lead to an increase in morbidity and mortality and a decrease in quality of life. The aim of this study was to analyse the profile of women with TS, who are currently followed in endocrinology, regarding: karyotype, age, final height and weight, puberty and fertility, and m...

Introduction: Struma ovarii is a rare form of ovarian teratoma mostly composed of thyroid tissue. In about 5% of the cases, well-differentiated thyroid carcinoma may arise in struma ovarii. As this medical entity is so exceptional, there is still no consensus on diagnosis and treatment.Case Reports: A 52-year-old old woman was submitted in 2009 to total hysterectomy with bilateral adnexectomy and pelvic lymphadenectomy. Histopathology r...

Introduction: Anti-Müllerian Hormone (AMH) is a useful marker of ovarian reserve (OR), since it remains stable inter/intra-cycles and presents a good correlation with ultrasonographic antral follicular count. Obesity/overweight are increasing and may affect the reproductive health. However, previous studies regarding the effect of body mass index (BMI) on AMH levels are discordant. Our main goal was to evaluate the influence of BMI in AMH levels in women with infertility....

Introduction: Estimated prevalence of hypertension (HT) in Portugal is 42%. It is a major risk factor for coronary heart disease and cerebrovascular disease, the leading mortality cause in Portugal. Primary aldosteronism (PA) was once recognized as rare cause of secondary hypertension and hypokalemia a condition present in all cases. Nowadays, prevalence of this condition is about 10% in HT patients, being the commonest form of secondary HT. Secondary forms of HT should be exc...

Background: Thyroid nodule in the pediatric age group is rare, but the rate of malignancy is much higher than adult population. Fine needle aspiration biopsy (FNAB) is an accurate test commonly used to determine whether thyroid nodules are malignant in adults. However, less is known about its diagnostic accuracy for this purpose in children.Aim: To characterize the outcomes of FNAB of nodular thyroid disease at a pediatric tertiary-care institution and t...

Background: Takotsubo cardiomyopathy is a rare, acute, nonischemic cardiomyopathy causing transient systolic disfunction of the apical and/or mid segments of left ventricle and is commonly associated with emotional and physical stress. Thyrotoxicosis is a rare cause of this condition, resulting from direct and indirect action of thyroid hormones on the cardiovascular system.Case presentation: A 43-year-old woman presented at emergency room with chest pai...

Introduction: Hypogonadism is common and occurs prematurely in human immunodeficiency virus (HIV)-infected men, being hypogonadotropic hypogonadism (HH) more frequent. However, HH with very low testosterone has not been described. We present three HIV-infected men with severe HH and normal pubertal development.Case report: Three HIV-infected men, with HIV-1 diagnosis at the ages of 22, 34 and 35 years. Two of them had depressive syndrome, one treated wit...

Introduction: The diagnosis of Cushing’s syndrome is often challenging considering that none of the used laboratory tests has an ideal diagnostic accuracy. The complexity of the diagnosis increases in cyclic disorder, which is characterized by repeated episodes of cortisol excess followed by periods of normal cortisol secretion.Case report: A 32-year-old woman with history of arterial hypertension and obesity presented with weight gain, hirsutism, a...

Introduction: The Bethesda System for Reporting Thyroid Cytopathology is the standard for interpreting fine-needle aspiration (FNA) and created a new diagnostic category (III): ‘atypia of undetermined significance/follicular lesion of undetermined significance’ (AUS/FLUS). The risk of malignancy for this category has been ascribed of 5–15% but the real malignancy rate remains unclear and plays a key role to define appropriate management.Ob...